Nicole Hazen died because of brain cancer

The Diamondbacks announced Thursday that Nicole Hazen, the wife of general manager Mike Hazen, has died at the age of 45

Hazen died of glioblastoma, an aggressive form of brain cancer, according to a family statement shared by the team

Nicole Hazen, pictured with Arizona Diamondbacks GM Mike Hazen and their four sons

Mike Hazen was hired as the Diamondbacks' general manager in 2016

She is survived by her husband, Mike, and their four sons, Charlie, John, Teddy and Sam